Posts for: February, 2017
Scientists have shown that chewing your food properly can boost your mouth's immune system to protect you against illness.
The study led by teams at The University of Manchester and National Institutes of Health in the USA, revealed that a specific type of immune cell, the Th17 cell, can be stimulated when you chew.
The immune cell is important in protecting against bacterial and fungal infections that are commonly found in the mouth .
Although it has long been known that the nutrients from food can support a healthy immune system the findings establish that the action of eating itself is important too.
In other parts of the body, such as the gut and skin, Th17 cells are stimulated by the presence of friendly bacteria; it was previously assumed this was the case in the mouth.
However, the team found that damage caused by the abrasion of chewing induced factors from the gums that could activate the same pathways as friendly bacteria and act upon Th17 cells.
However, stimulation of Th17 cells for immune protection can be a double-edged sword: too many Th17 cells can contribute to periodontitis – a common gum disease that is linked to complications in lots of diseases including diabetes, rheumatoid arthritis, heart problems and pre-term birth.
The research was funded by the BBSRC and National Institute of Dental and Craniofacial Research in the United States
Lead researcher and biologist Dr Joanne Konkel, from The University of Manchester, said: "The immune system performs a remarkable balancing act at barrier sites such as the skin, mouth and gut by fighting off harmful pathogens while tolerating the presence of normal friendly bacteria.
"Our research shows that, unlike at other barriers, the mouth has a different way of stimulating Th17 cells: not by bacteria but by mastication. Therefore mastication can induce a protective immune response in our gums".